4020) Layout of Playlots

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Thirty years after the untimely death of Imre Lakatos, the enduring influence of several Lakatosian issues and ideas asks for a systematic appraisal of his work. A significant step in this direction has been made in two workshops, organized by the Institute Vienna Circle and the Institute for History and Philosophy of Science of Eötvös University, which were held in Vienna and Budapest in Autum...

Pii: S0040-4020(00)00949-2

ÐCuticle sclerotization or tanning is a vital process that occurs during each stage of insect development to harden and stabilize the newly secreted exoskeleton. The structural polymers protein and chitin make up the bulk of the cuticle, and chemical interactions between these biopolymers with quinonoid tanning agents are largely responsible for the physical properties of the mature exoskeleton...

Pii: S0040-4020(99)00950-3

Pii: S0040-4020(97)00801-6

The synthesis of two classes of Philanthotoxin-343 analogs is described. Quantitative information on the antagonism of quisqualate-sensitive ionotropic glutamate receptors of insect muscle by these compounds is presented. © 1997 Elsevier Science Ltd.

Pii: S0040-4020(00)00525-1

ÐPhotocleavage of proteins by a series of organic probe molecules is examined as a function of probe structure. For example, pyrenyl peptides Py-Gly-X (XˆTrp, Tyr, Phe, and His, and Pyˆ4(1-pyrenyl)butyroyl)) are prepared, and their protein binding/photocleavage properties have been examined. The binding constants with bovine serum albumin (BSA) are in the range of 10 to 10 and binding of the pr...